Makerere University Walter Reed Project (MUWRP) is a non-profit biomedical research organization, whose mission is to mitigate disease threats through quality research, health care and disease surveillance. MUWRP was established in 2002 by a Memorandum of Agreement between The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HUF) and Makerere University (Mak) to undertake medical research to test HIV vaccines. Over the years, MUWRP’s portfolio has progressively expanded to include vaccine research for Ebola and Marburg viruses, Emerging Infectious Diseases Program (EIDP) for surveillance of influenza and influenza-like viruses and other emerging infections in humans and animals; also, a PEPFAR funded program in HIV treatment, care and prevention in the districts of Kayunga, Mukono, Buvuma and Buikwe. Additionally, MUWRP in collaboration with local and international partners is implementing The Joint Mobile Emerging Disease Intervention Clinical Capability (JMEDICC) program in Uganda whose purpose is to conduct FDA regulated clinical trials of therapeutics or diagnostics during an outbreak event of high consequence pathogens specifically filoviruses.